13 pages. Sets out thirteen variables that move a susceptibility result, each with the requirement and the direction the error runs, so that staff can recognize a systematic shift before it reaches a report. Covers reference and supplementary strains, conversion to and loss of reduced frequency testing, a nine step response to an out of range result, controls for eight confirmatory tests, and confirmation of implausible phenotypes before release. Includes interpretive standard version control and annual breakpoint implementation